Botez M I, Joyal C, Maag U, Bachevalier J
Can J Neurol Sci. 1982 Feb;9(1):37-9. doi: 10.1017/s0317167100043602.
Thiamine and folate levels in blood and cerebrospinal fluid (CSF) were determined by microbiological assays in 23 control subjects and 11 phenytoin-treated epileptics. There was no significant difference between the two groups for serum and CSF folate levels. There was, however, a statistically significant difference between the groups for both whole blood thiamine and CSF thiamine levels. Epileptic patients being treated with phenytoin had lower values than control subjects.
