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伴有重症肌无力的转移性胸腺瘤:联合化疗实现完全缓解

Metastatic thymoma with myasthenia gravis: complete remission with combination chemotherapy.

作者信息

Butler W M, Diehl L F, Taylor H G, Weltz M D

出版信息

Cancer. 1982 Aug 1;50(3):419-22. doi: 10.1002/1097-0142(19820801)50:3<419::aid-cncr2820500306>3.0.co;2-a.

DOI:10.1002/1097-0142(19820801)50:3<419::aid-cncr2820500306>3.0.co;2-a
PMID:7093885
Abstract

A 29-year-old male developed myasthenia gravis 29 months after resection of a "benign" mediastinal thymoma. Metastatic thymoma was found in the pleura 45 months after the initial surgical resection. Combination chemotherapy with cyclophosphamide and doxorubicin produced a complete remission of the metastatic thymoma which has continued for 13 months. Concurrently, there has been a marked increase in neuromuscular function.

摘要

一名29岁男性在切除“良性”纵隔胸腺瘤29个月后发生重症肌无力。初次手术切除45个月后,在胸膜发现转移性胸腺瘤。环磷酰胺和阿霉素联合化疗使转移性胸腺瘤完全缓解,持续了13个月。同时,神经肌肉功能有显著改善。

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Metastatic thymoma with myasthenia gravis: complete remission with combination chemotherapy.伴有重症肌无力的转移性胸腺瘤:联合化疗实现完全缓解
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Remission of myasthenia gravis in association with unresectable, invasive thymoma.重症肌无力缓解与不可切除的侵袭性胸腺瘤相关。
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Successful salvage chemotherapy with amrubicin for invasive thymoma associated with myasthenia gravis.使用氨柔比星成功挽救性化疗治疗与重症肌无力相关的侵袭性胸腺瘤。
Jpn J Clin Oncol. 2014 Nov;44(11):1120-2. doi: 10.1093/jjco/hyu136. Epub 2014 Sep 19.

引用本文的文献

1
Thymoma and thymic carcinoma.胸腺瘤和胸腺癌。
Gen Thorac Cardiovasc Surg. 2012 Jan;60(1):1-12. doi: 10.1007/s11748-011-0814-0. Epub 2012 Jan 13.
2
Thymomas. Current experience and future directions in therapy.胸腺瘤。治疗的当前经验与未来方向
Drugs. 1993 Apr;45(4):477-87. doi: 10.2165/00003495-199345040-00001.
3
Thymoma presenting as a superior vena cava syndrome remission following therapy.胸腺瘤表现为治疗后上腔静脉综合征缓解。
Klin Wochenschr. 1987 Jul 1;65(13):617-9. doi: 10.1007/BF01726671.