Volicer L, Volicer B J
Clin Exp Hypertens A. 1982;4(6):849-65. doi: 10.3109/10641968209060758.
Adverse effects of alcohol drinking were investigated in 240 hypertensive patients. Perceived interaction between alcohol and antihypertensive medication was reported by 9.9% of patients but the symptoms were rather mild. Except for the fact that the patients who perceived drug-alcohol interaction had higher diastolic blood pressure than the rest of the patients there was no evidence that alcohol use decreased compliance with antihypertensive treatment. Most heavy alcohol users believed that they should take their antihypertensive medication while drinking and reported doing so. Indiscriminate emphasis on avoidance of drug-alcohol combination might decrease blood pressure control of these patients.
对240名高血压患者饮酒的不良反应进行了调查。9.9%的患者报告了酒精与抗高血压药物之间的相互作用,但症状相当轻微。除了那些察觉到药物-酒精相互作用的患者舒张压高于其他患者这一事实外,没有证据表明饮酒会降低抗高血压治疗的依从性。大多数重度饮酒者认为他们在饮酒时应该服用抗高血压药物,并报告他们确实这样做了。不加区分地强调避免药物与酒精联用可能会降低这些患者的血压控制效果。