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沙丁胺醇治疗的住院抑郁症患者临床变化的定性研究(作者译)

[A qualitative study of clinical change in population of salbutamol-treated hospitalized depressives (author's transl)].

作者信息

Manceaux D, Lecrubier Y, Jouvent R

出版信息

Encephale. 1982;8(1):25-35.

PMID:7094870
Abstract

On the basis of pharmacological and clinical findings, salbutamol, a beta-adrenergic stimulant, is used in the treatment of depression. The day by day evolution of each of the most commonly evaluated symptoms in depressed patients is presented as observed during 10 days in 13 patients who were administered this treatment. Improvement appears to be global: it concerns all symptoms. However: - improvement of psychomotor retardation is early and is often observed before mood recovery; - and anxiety seems to variate independently from other factors. Responding patients were those who presented a frank depressive state with no associated psychiatric pathology. Tolerance was satisfactory in all cases.

摘要

基于药理学和临床研究结果,β-肾上腺素能兴奋剂沙丁胺醇被用于治疗抑郁症。本文呈现了13例接受该治疗的患者在10天内观察到的抑郁症患者最常评估的各项症状的逐日变化情况。改善似乎是全面的:涉及所有症状。然而: - 精神运动迟缓的改善较早出现,且常在情绪恢复之前就可观察到; - 而焦虑似乎独立于其他因素而变化。有反应的患者是那些呈现出无相关精神病理学的明显抑郁状态的患者。所有病例的耐受性均令人满意。

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