Rossini F P, Ferrari A, Spandre M, Coverlizza S
Endoscopy. 1982 Jul;14(4):124-7. doi: 10.1055/s-2007-1021598.
Of 1696 endoscopically removed polyps in the authors' series 62% were adenomas and 31 showed invasive carcinoma. 8 patients were not available for follow-up, and 7 underwent surgical resection with negative findings. There was no evidence of recurrent cancer in the remaining 16 over a 1-6 year span of follow-up, although one unrelated rectal carcinoma and an adenoma were found. By combining the data of 10 Italian Centres, 44 further patients were available, who had had endoscopic polypectomy as the only management of cancerous adenomas, adding no additional example of recurrent carcinoma. It is concluded that endoscopic polypectomy can, providing strict histological criteria are satisfied, provide definitive resection of some cancerous adenomas. A detailed follow-up regime including physical examination, occult blood testing, repeated endoscopy, paired tumour antigen levels and ultrasonography has been used to confirm the absence of recurrence in our series.
在作者的病例系列中，1696例经内镜切除的息肉中，62%为腺瘤，31例显示浸润性癌。8例患者无法进行随访，7例接受了手术切除，结果为阴性。在1 - 6年的随访期内，其余16例患者没有癌症复发的证据，不过发现了1例无关的直肠癌和1例腺瘤。通过合并10个意大利中心的数据，又有44例患者可供研究，他们接受了内镜息肉切除术，作为癌性腺瘤的唯一治疗方法，未增加复发性癌的其他病例。结论是，只要满足严格的组织学标准，内镜息肉切除术可以对一些癌性腺瘤进行根治性切除。我们采用了详细的随访方案，包括体格检查、潜血检测、重复内镜检查、成对肿瘤抗原水平检测和超声检查，以确认我们的病例系列中没有复发情况。
