Di Febo G, Milazzo G, Gizzi G, Biasco G, Miglioli M
Endoscopy. 1982 Jul;14(4):128-30. doi: 10.1055/s-2007-1021599.
Among the 14 cases of antibiotic-induced colitis, endoscopic features were: in 9 cases typical pseudomembranes, in 4 cases petechiae or ecchymosis or suggillation-like redness with near-to-normal surrounding mucosa. In one case induced by Spiramycin, a macrolide that had never been previously indicated as being responsible for the disease, the endoscopic picture was 'atypical' and directed us towards a severe ulcerative colitis. These forms are very rare and usually limited to the right or transverse colon which suggests, if possible, a total colonoscopy. The nosographic picture of these cases is not quite clear, since they could represent both the most severe stages within 'non-pseudomembranous' antibiotic-induced colitis and autonomous forms whose evolution does not contribute in any way to the formation of pseudomembranes.
在14例抗生素相关性结肠炎病例中，内镜特征如下：9例有典型假膜，4例有瘀点、瘀斑或类似紫癜样发红，周围黏膜接近正常。在1例由螺旋霉素（一种此前从未被指出可导致该病的大环内酯类药物）引起的病例中，内镜表现“不典型”，使我们考虑为重度溃疡性结肠炎。这些类型非常罕见，通常局限于右半结肠或横结肠，这提示如有可能应进行全结肠镜检查。这些病例的疾病分类情况尚不完全清楚，因为它们可能既代表“非假膜性”抗生素相关性结肠炎的最严重阶段，也代表其演变过程与假膜形成毫无关系的独立类型。
