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肾皮质肾小管离子置换过程中的电压瞬变。

Voltage transients during ionic substitution in renal cortical tubules.

作者信息

Lopes A G, de Mello G B, Malnic G

出版信息

Experientia. 1982 May 15;38(5):588-90. doi: 10.1007/BF02327064.

DOI:10.1007/BF02327064
PMID:7095094
Abstract

A voltage transient is described which is found during proximal tubular perfusion with impermeant cation or anion salt solutions in the rat. It was shown that the magnitude of transepithelial diffusion potentials depended on luminal hydrostatic pressure, suggesting that the observed transients might be the consequence of the enlargement of ionic pathways by tubular dilatation. Thus, when reporting PD values, care should be taken to define the pressure levels at which measurements were performed.

摘要

描述了一种电压瞬变现象,该现象是在大鼠近端肾小管灌注非渗透性阳离子或阴离子盐溶液过程中发现的。结果表明,跨上皮扩散电位的大小取决于管腔内静水压,这表明观察到的瞬变现象可能是肾小管扩张导致离子通道扩大的结果。因此,在报告PD值时,应注意明确进行测量时的压力水平。

相似文献

1
Voltage transients during ionic substitution in renal cortical tubules.肾皮质肾小管离子置换过程中的电压瞬变。
Experientia. 1982 May 15;38(5):588-90. doi: 10.1007/BF02327064.
2
Transepithelial and cell membrane electrical resistances of the rabbit proximal convoluted tubule.兔近端曲小管的跨上皮电阻和细胞膜电阻
Am J Physiol. 1984 Oct;247(4 Pt 2):F637-49. doi: 10.1152/ajprenal.1984.247.4.F637.
3
Conductances, diffusion and streaming potentials in the rat proximal tubule.大鼠近端肾小管中的电导、扩散和流动电位。
J Physiol. 1976 Sep;260(3):553-69. doi: 10.1113/jphysiol.1976.sp011531.
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Ca2+ absorption in the pars recta of cortical S2 rabbit proximal tubules: role of diffusion.皮质S2兔近端小管直部的Ca2+吸收:扩散的作用
Am J Physiol. 1989 Aug;257(2 Pt 2):F262-7. doi: 10.1152/ajprenal.1989.257.2.F262.
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Isolated perfused salamander proximal tubule: methods, electrophysiology, and transport.离体灌注蝾螈近端小管:方法、电生理学与转运
Am J Physiol. 1981 Jul;241(1):F39-52. doi: 10.1152/ajprenal.1981.241.1.F39.
6
Electrical resistance of cell membranes in Necturus kidney.美西螈肾脏细胞膜的电阻
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A parallel path model for Necturus proximal tubule.美西螈近端小管的平行路径模型。
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Intracellular ion activities in Necturus proximal tubule.美西螈近端小管中的细胞内离子活性。
Fed Proc. 1979 Dec;38(13):2729-32.

本文引用的文献

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ELECTRICAL EXCITABILITY OF ISOLATED FROG SKIN AND TOAD BLADDER.离体蛙皮和蟾蜍膀胱的电兴奋性
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[Effect of furosemid and NaCl-loading on chloride excretion in single nephrons of rat kidneys].[呋塞米和氯化钠负荷对大鼠肾脏单个肾单位氯排泄的影响]
Pflugers Arch. 1969;309(1):21-37. doi: 10.1007/BF00592279.
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Action potentials induced in biomolecular lipid membranes.生物分子脂质膜中诱导产生的动作电位。
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Hydrostatic pressure in the rat kidney.大鼠肾脏中的流体静压。
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6
Pressure control of sodium reabsorption and intercellular backflux across proximal kidney tubule.近端肾小管钠重吸收及细胞间反流的压力控制
J Clin Invest. 1974 Jul;54(1):69-82. doi: 10.1172/JCI107751.
7
Electrical phenomena in the nephron.
Kidney Int. 1976 Feb;9(2):88-102. doi: 10.1038/ki.1976.14.
8
Conductances, diffusion and streaming potentials in the rat proximal tubule.大鼠近端肾小管中的电导、扩散和流动电位。
J Physiol. 1976 Sep;260(3):553-69. doi: 10.1113/jphysiol.1976.sp011531.