Unsöld R
Graefes Arch Clin Exp Ophthalmol. 1982;218(3):124-38. doi: 10.1007/BF02215649.
Computed tomograms of 166 optic nerve lesions were analyzed: 97 were mainly orbital and 69 mainly intracranial. The criteria were clinical course, size, density and delineation of the optic nerve shadow, orbital and cerebral soft tissue abnormalities, and bony changes in the optic canal. Characteristic CT features are described of individual disease entities such as optic gliomas, optic nerve sheath meningiomas, neoplastic and inflammatory infiltrations. The differential diagnostic importance of individual CT criteria is evaluated and discussed. Simultaneous visualization of orbital and intracranial soft tissue changes as well as bony changes in the optic canal allow the location and identification of the majority of optic nerve lesions based on the criteria mentioned above, and optic nerve tumors can be differentiated. In 9 patients with optic neuritis due to clinically proven encephalitis and in 17 patients with total optic atrophy, no changes in the size of the optic nerve could be found. CT evaluation of the intraorbital portion of the optic nerve requires special examination techniques. Oblique computer reformations through the optic canal provide excellent visualization of bony changes in the optic canal. The exclusion of intracranial causes of optic nerve lesions requires intravenous injection of contrast material.
对166例视神经病变的计算机断层扫描图像进行了分析:其中97例主要位于眼眶,69例主要位于颅内。评判标准包括临床病程、大小、密度、视神经阴影的轮廓、眼眶及脑内软组织异常以及视神经管的骨质改变。文中描述了视神经胶质瘤、视神经鞘膜瘤、肿瘤性及炎性浸润等个别疾病实体的特征性CT表现。对各项CT标准在鉴别诊断中的重要性进行了评估和讨论。眼眶及颅内软组织改变以及视神经管骨质改变的同时显示,有助于根据上述标准对大多数视神经病变进行定位和识别,并可鉴别视神经肿瘤。在9例经临床证实为脑炎所致视神经炎患者及17例完全性视神经萎缩患者中,未发现视神经大小改变。对视神经眶内段进行CT评估需要特殊的检查技术。通过视神经管的斜位计算机重建可清晰显示视神经管的骨质改变。排除视神经病变的颅内病因需要静脉注射造影剂。