Buhles N, Altmeyer P
Fortschr Med. 1982 May 13;100(18):859-63.
The most important morphological aspects and pathogenesis of necrobiosis lipoidica concerning histological and clinical aspects are reported. In case of diabetes we find more frequently necrobiosis lipoidica localized out of the shank than in cases of necrobiosis lipoidica without diabetes. Necrobiosis lipoidica must be differentiated from granulomatosis disciformis, localized scleroderma and atrophy of the skin of another origin. Beside normalization of diabetes and application of corticosteroids physical and surgical treatment is recommended.
本文报道了有关类脂质渐进性坏死的组织学和临床方面最重要的形态学表现及发病机制。在糖尿病患者中,相比于非糖尿病患者中的类脂质渐进性坏死,我们更常发现其位于小腿以外的部位。类脂质渐进性坏死必须与盘状肉芽肿、局限性硬皮病及其他原因引起的皮肤萎缩相鉴别。除了控制糖尿病和应用皮质类固醇外,还建议采用物理和手术治疗。