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乙酰化表型与单胺氧化酶抑制剂治疗的关系:综述

The relationship of acetylation phenotype to treatment with MAOIs: a review.

作者信息

Rose S

出版信息

J Clin Psychopharmacol. 1982 Jun;2(3):161-4.

PMID:7096607
Abstract

The English language literature that addresses the relationship between acetylation phenotype and clinical response to monoamine oxidase inhibitors is reviewed. In all, seven studies have been published in the last 20 years. Historical antecedents leading to interest in the relationship between acetylation phenotype and monoamine oxidase inhibitors are examined. Each study is then summarized, with comments about its relative merits and deficiencies. The review concludes that the data published do not support the notion of a correlation between acetylation phenotype and clinical response to monoamine oxidase inhibitors.

摘要

本文综述了探讨乙酰化表型与单胺氧化酶抑制剂临床反应之间关系的英文文献。在过去20年里,总共发表了7项研究。本文考察了引发人们对乙酰化表型与单胺氧化酶抑制剂之间关系产生兴趣的历史背景。随后对每项研究进行了总结,并对其相对优点和不足进行了评论。该综述得出结论,已发表的数据并不支持乙酰化表型与单胺氧化酶抑制剂临床反应之间存在相关性的观点。

相似文献

1
The relationship of acetylation phenotype to treatment with MAOIs: a review.乙酰化表型与单胺氧化酶抑制剂治疗的关系:综述
J Clin Psychopharmacol. 1982 Jun;2(3):161-4.
2
Monoamine oxidase-inhibiting antidepressants. A clinical update.单胺氧化酶抑制性抗抑郁药。临床最新进展。
Psychiatr Clin North Am. 1984 Sep;7(3):549-62.
3
An open trial of MAO inhibitors in bulimia.一项关于单胺氧化酶抑制剂治疗贪食症的开放性试验。
J Clin Psychiatry. 1984 May;45(5):217-9.
4
Phenelzine use throughout pregnancy and the puerperium: case report, review of the literature, and management recommendations.孕期及产褥期使用苯乙肼:病例报告、文献综述及管理建议
Depress Anxiety. 1997;6(3):124-8.
5
[Abuse of the monoamine oxidase (MAOI) inhibitors as antidepressive drugs: a critical review].[单胺氧化酶(MAOI)抑制剂作为抗抑郁药物的滥用:批判性综述]
Actas Luso Esp Neurol Psiquiatr Cienc Afines. 1995 Jul-Aug;23(4):217-22.
6
Monoamine oxidase inhibitors for depressed cardiac patients.用于抑郁症心脏病患者的单胺氧化酶抑制剂。
J Clin Psychiatry. 1985 Dec;46(12):545-6.
7
[Classical monoamine oxidase inhibitor: not registered for, but still a place in the treatment of depression].[经典单胺氧化酶抑制剂:未注册用于治疗抑郁症,但在抑郁症治疗中仍占有一席之地]
Ned Tijdschr Geneeskd. 2003 Oct 4;147(40):1940-3.
8
Coadministration of phenelzine and methylphenidate for treatment-resistant depression.
Ann Pharmacother. 2004 Mar;38(3):508. doi: 10.1345/aph.1D115. Epub 2004 Jan 23.
9
Phenelzine as a possible treatment for depression in schizophrenic patients.苯乙肼作为精神分裂症患者抑郁症的一种可能治疗方法。
Isr J Psychiatry Relat Sci. 1996;33(3):211-2.
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'Spontaneous' hypertensive episodes with monoamine oxidase inhibitors.单胺氧化酶抑制剂引发的“自发性”高血压发作。
J Clin Psychiatry. 1988 Apr;49(4):163-5.

引用本文的文献

1
Genetically determined variability in acetylation and oxidation. Therapeutic implications.乙酰化和氧化的基因决定变异性。治疗意义。
Drugs. 1985 Apr;29(4):342-75. doi: 10.2165/00003495-198529040-00003.
2
Insights into the mechanisms of action of the MAO inhibitors phenelzine and tranylcypromine: a review.单胺氧化酶抑制剂苯乙肼和反苯环丙胺作用机制的研究进展:综述
J Psychiatry Neurosci. 1992 Nov;17(5):206-14.