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尸检时的药物检测:247例前瞻性研究。

Drug detection at autopsy: a prospective study of 247 cases.

作者信息

Norton L E, Garriott J C, DiMaio V J

出版信息

J Forensic Sci. 1982 Jan;27(1):66-71.

PMID:7097197
Abstract

Comprehensive toxicology analyses using gas chromatography of blood for alcohol and acidic, basic, and neutral drugs were performed on 247 randomly selected medical examiner cases. Drugs or alcohol or both were found in 54% of this group. When considered by manner of death (natural, accident, homicide, and suicide), each of the groups had incidences of positive findings of 46 to 63%. Selection of cases for toxicologic study on the basis of manner of death does not seem to be feasible. It is the authors' opinion that comprehensive toxicology evaluation for drugs should be done on virtually all medical examiner cases. This approach ensures a thorough and complete evaluation in all cases. In addition, a comprehensive toxicology study will provide information in the event that questions concerning the absence or presence of drugs arise at some later date.

摘要

对247例随机选取的法医案件进行了全面的毒理学分析,采用气相色谱法检测血液中的酒精以及酸性、碱性和中性药物。该组中有54%的案件检测出药物、酒精或两者皆有。按死亡方式(自然死亡、意外死亡、他杀和自杀)分类考虑时,每组的阳性检出率为46%至63%。基于死亡方式选择毒理学研究病例似乎不可行。作者认为,几乎所有法医案件都应进行全面的药物毒理学评估。这种方法可确保对所有案件进行彻底和全面的评估。此外,全面的毒理学研究将在日后出现有关药物是否存在的问题时提供信息。

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Assessing the autopsy.评估尸检情况。
Am J Pathol. 1987 Aug;128(2):362-79.