Stammberger H
Laryngol Rhinol Otol (Stuttg). 1982 May;61(5):234-7.
Two cases of argyrosis of the nasal mucosa are described and special histological features of the silver particle in tissue-samples were demonstrated. One of the patients had inhalative contact with silveroxide preparations for at least 6 years; in the second case the local argyrosis was associated with a malignant lymphoma of the nasopharynx. Due to patient non-compliance no further investigations could be made to evaluate a cancerogenic influence of the metal pigment. A description of other possible exogenic and endogenic pigments is given with special emphasis on cancerogenic effects.
本文描述了两例鼻黏膜银质沉着症病例，并展示了组织样本中银颗粒的特殊组织学特征。其中一名患者与氧化银制剂有至少6年的吸入接触；在第二例中，局部银质沉着症与鼻咽癌相关。由于患者不配合，无法进行进一步调查以评估金属色素的致癌影响。文中还介绍了其他可能的外源性和内源性色素，并特别强调了致癌作用。
