Scott W N, Dines D M, Insall J N
Clin Orthop Relat Res. 1978 Sep(135):42-4.
The skeletal system manifestations of thalassemia are characterized by severe osteoporosis, frequent fractures and delayed healing. Permanent deformity and disability can complicate the fractures. Surgical correction of deformity by osteotomy of severely osteoporotic bone and immobilization without internal fixation was successful in a 20-year-old woman. While operative correction of deformity is not routinely recommended, the good experience with this case suggests that similar orthopedic procedures can be included in the treatment of thalassemia.
地中海贫血的骨骼系统表现特征为严重骨质疏松、频繁骨折和愈合延迟。骨折可能会并发永久性畸形和残疾。一名20岁女性通过对严重骨质疏松的骨骼进行截骨术来手术矫正畸形并在不进行内固定的情况下进行固定，手术取得了成功。虽然通常不建议对畸形进行手术矫正，但该病例的良好经验表明，类似的骨科手术可纳入地中海贫血的治疗中。
