Blagosklonnaia Ia V, Mamedov R, Kozlov V V, Emanuél' V L, Kudriashova M I
Probl Endokrinol (Mosk). 1982 May-Jun;28(3):3-8.
Effect of trental on some renal function parameters was studied in 11 patients with diabetes mellitus, 7 of these patients had clinical signs of diabetic nephropathy. Trental was administered by intravenous drip in a dose of 300 mg daily during 3 weeks. Marked improvement of renal function under the effect of trental was recorded: glomerular filtration increased, proteinuria diminished, and the level of glycemia reduced. No side effects of trental treatment were observed. It is suggested that trental be used in comprehensive treatment of diabetes mellitus patients
研究了曲克芦丁对11例糖尿病患者某些肾功能参数的影响,其中7例患者有糖尿病肾病的临床症状。曲克芦丁通过静脉滴注给药,剂量为每日300毫克,持续3周。记录到在曲克芦丁作用下肾功能有明显改善:肾小球滤过增加,蛋白尿减少,血糖水平降低。未观察到曲克芦丁治疗的副作用。建议将曲克芦丁用于糖尿病患者的综合治疗。