Carlotti M E, Trotta M, Gasco M R
Pharmazie. 1982 Mar;37(3):194-6.
Complexation between oppositely charged antidepressant drugs and porphyrin derivatives was investigated by NMR spectroscopy. The solid complexes obtained are soluble in antidepressant aggregates and a good fit was found between the values of CMC of the drugs and the values of the binding constants of porphyrins with antidepressant micelles.
通过核磁共振光谱研究了带相反电荷的抗抑郁药物与卟啉衍生物之间的络合作用。所得到的固体络合物可溶于抗抑郁聚集体中,并且发现药物的临界胶束浓度值与卟啉与抗抑郁胶束的结合常数之间具有良好的拟合度。