Ganske J G, Demuth R J, Miller S H, Buck D C, Dolph J L
Plast Reconstr Surg. 1982 Aug;70(2):193-201. doi: 10.1097/00006534-198208000-00013.
The use of 1-mm ID by 1-cm-long expanded polytetrafluoroethylene microvascular grafts in various positions in two experimental animals did not compare favorably with the use of autogenous vein interposition grafts in controls. Light microscopy and scanning electron microscopy showed that early fibrin deposition at the anastomosis lines is followed by fully activated coagulation of the grafts. Use of antiplatelet and anticoagulant drugs, changes in techniques, and alterations in the graft material are possible future directions for improved patency with expanded polytetrafluoroethylene microvascular grafts.
在两只实验动物的不同部位使用内径1毫米、长度1厘米的膨体聚四氟乙烯微血管移植物，与对照组使用自体静脉搭桥移植物相比，效果不佳。光学显微镜和扫描电子显微镜显示，吻合线处早期有纤维蛋白沉积，随后移植物完全激活凝血。使用抗血小板和抗凝药物、技术改进以及移植物材料改变，可能是提高膨体聚四氟乙烯微血管移植物通畅率的未来发展方向。
