Jaeger M J
Respir Physiol. 1982 Mar;47(3):325-40. doi: 10.1016/0034-5687(82)90061-5.
The distensibility of the upper airways was found to range in 8 subjects between 0.01 and 0.001 L/cm H2O. This distensibility may cause a number of errors in standard respiratory measurements in normal subjects and in patients with airway obstruction due to delays in pressure and flow equilibration between alveoli and mouth. The error include overestimation of thoracic gas volume with the body plethysmograph; of airway inertance and of dynamic lung compliance; underestimation of respiratory resistance with the forced oscillation technique and with interruption pressure; underestimation of total pressure exerted by respiratory muscles with the P o.1 technique during occlusions of the airway opening. The errors are often quite appreciable and may exceed 100%. Ways to reduce them or to compensate for them are discussed.
研究发现，8名受试者上呼吸道的扩张性在0.01至0.001升/厘米水柱之间。由于肺泡与口腔之间压力和流量平衡存在延迟，这种扩张性可能在正常受试者和气道阻塞患者的标准呼吸测量中导致一些误差。这些误差包括：使用体容积描记器时对胸腔气体容积的高估；对气道惯性和动态肺顺应性的高估；使用强迫振荡技术和阻断压力时对呼吸阻力的低估；在气道开口阻塞期间使用P0.1技术时对呼吸肌施加的总压力的低估。这些误差通常相当可观，可能超过100%。文中讨论了减少或补偿这些误差的方法。
