Tominaga I, Kato Y, Tanaka S, Nakahara Y, Isohisa I, Miura I
Rev Neurol (Paris). 1982;138(2):159-68.
A 38-year-old woman with encephalitis presented no signs of infectious disease or exanthema. After a remission lasting 10 months, she died during a second attack after demonstrating signs of brain stem lesions. Histological examination revealed lesions, mainly in the brain stem and characterized by intense necrosis, moderate degrees of inflammation, and localized foci of gliosis. In spite of the necrotic lesions, the neurones were relatively spared. An old infarct of the left caudate nucleus was present. Taking other demyelinating diseases into account, it is suggested that this is a clinical form of multiple sclerosis, this enabling a relationship to be established between multiple sclerosis and post-infections perivenous encephalitis or acute disseminated encephalomyelitis.
一名38岁的脑炎女性患者没有感染性疾病或皮疹的迹象。在持续缓解10个月后，她在第二次发作时出现脑干病变迹象后死亡。组织学检查发现病变主要位于脑干，其特征为严重坏死、中度炎症和局部胶质增生灶。尽管有坏死性病变，但神经元相对未受影响。左侧尾状核有陈旧性梗死灶。考虑到其他脱髓鞘疾病，提示这是多发性硬化的一种临床形式，这使得多发性硬化与感染后静脉周围脑炎或急性播散性脑脊髓炎之间建立了联系。
