Molthan L
Rev Fr Transfus Immunohematol. 1982 Apr;25(2):127-47. doi: 10.1016/s0338-4535(82)80002-0.
The biological significance of alloantibodies directed against the red blood cell antigens York, Cost, McCoy, and Knops has been investigated by means of a literature search and an analysis of 304 patient referrals received since 1965. Neither method detected documented cases of erythroblastosis fetalis due to these antibodies. The analysis of the patient referrals identified 11 women immunized by pregnancy. The literature search provided one documented case of hemolytic transfusion reaction and one probable case of successful transfusion of incompatible blood. The analysis of the patient referrals revealed two cases of probable successful transfusions of incompatible blood, nine patients with documented evidences of extravascular hemolytic transfusion reactions, and one patient with documented evidence of intravascular hemolytic transfusion reaction. The conclusion reached is that alloantibodies directed against the York, Cost, McCoy, and Knops antigens are biologically significant with respect to red blood cell transfusions in some patients. Transfusion practices show that most patients have received compatible transfusions, an indication that the physicians in the hospitals adhere to the philosophy of compatible transfusions, whenever possible.
通过文献检索以及对自1965年以来收到的304例患者转诊病例的分析，研究了针对红细胞抗原York、Cost、McCoy和Knops的同种抗体的生物学意义。两种方法均未检测到因这些抗体导致的胎儿成红细胞增多症的记录病例。对患者转诊病例的分析确定了11名因妊娠而产生免疫的女性。文献检索提供了1例溶血性输血反应的记录病例和1例可能成功输注不相容血液的病例。对患者转诊病例的分析显示了2例可能成功输注不相容血液的病例、9例有血管外溶血性输血反应记录证据的患者以及1例有血管内溶血性输血反应记录证据的患者。得出的结论是，针对York、Cost、McCoy和Knops抗原的同种抗体在某些患者的红细胞输血方面具有生物学意义。输血实践表明，大多数患者接受了相容的输血，这表明医院的医生尽可能坚持相容输血的理念。
