Nádvorník F, Lysenková A
Soud Lek. 1982 May;27(2):17-26.
In a group of 40 cerebral contusions with a different period of survival by histological and histochemical methods changes in the contusion foci and their surroundings were assessed. The authors compared their own findings with those of other authors. Their finding of leucostasis and incipient leucodiapedesis was found in cerebral contusions with 7 hours survival. A more marked incidence of leucocytes near the contusion was in cases with a survival of 30 hours. A readily apparent gliomensenchymal reaction near the contusion focus was found in patients who survived the injury for eight days. In the glial elements acid phosphatase and no-specific esterase activity was detected. In contusion of the frontal lobe with a 13-day survival considerable cellulization and increase in the amount of capillaries was found near the contusion focus. In survival of contusion of the frontal lobe for 28 days the glial elements with an acid phosphatase and non-specific esterase activity form a margin round the contusion focus. Even in contusion of the frontal lobe with 5-month survival numerous granular cells were found in the neighbouring area. The results obtained by the authors are not always consistent with those of others. The data of other authors frequently vary too. Therefore it is important to be careful about estimates of the age of cerebral contusions and in particular in cerebral contusions with longer survival the estimate of the age of the injury is only approximate.
通过组织学和组织化学方法，对40例不同存活时间的脑挫伤患者进行研究，评估挫伤灶及其周围的变化。作者将自己的研究结果与其他作者的进行了比较。他们发现在存活7小时的脑挫伤中存在白细胞停滞和早期白细胞渗出。在存活30小时的病例中，挫伤附近白细胞的发生率更高。在受伤存活8天的患者中，在挫伤灶附近发现了明显的神经胶质-间质反应。在神经胶质成分中未检测到酸性磷酸酶和非特异性酯酶活性。在额叶挫伤存活13天的病例中，在挫伤灶附近发现了大量细胞化和毛细血管数量增加。在额叶挫伤存活28天的病例中，具有酸性磷酸酶和非特异性酯酶活性的神经胶质成分在挫伤灶周围形成一个边缘。即使在额叶挫伤存活5个月的病例中，在邻近区域也发现了大量颗粒细胞。作者获得的结果并不总是与其他作者的一致。其他作者的数据也经常变化。因此，在估计脑挫伤的时间时要谨慎，特别是在存活时间较长的脑挫伤中，损伤时间的估计只是大致的。
