人脐静脉来源的培养内皮细胞产生的纤溶抑制剂的部分特性研究
Partial characterization of a fibrinolytic inhibitor produced by cultured endothelial cells derived from human umbilical vein.
作者信息
Esnard F, Dupuy E, Dosne A M, Bodevin E
出版信息
Thromb Haemost. 1982 Apr 30;47(2):128-31.
PMID:7101231
Abstract
A preliminary characterization of a fibrinolytic inhibitor released by human umbilical vein endothelial cells in primary culture is reported. This molecule of Mr comprised between 2 X 10(5) and 10(6) and of alpha 2 mobility precipitates at 43% ammonium sulphate saturation and is totally adsorbed on Concanavalin A Sepharose 4 B. A possible relationship with alpha macroglobulins is discussed.
摘要
报道了对原代培养的人脐静脉内皮细胞释放的一种纤溶抑制剂的初步特性研究。该分子的相对分子质量在2×10⁵至10⁶之间，具有α₂迁移率，在43%硫酸铵饱和度下沉淀，并且完全吸附在伴刀豆球蛋白A琼脂糖4B上。讨论了其与α巨球蛋白的可能关系。
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