Lyberg T, Hetland O, Prydz H
Thromb Haemost. 1982 Apr 30;47(2):154-6.
The established murine macrophage cell line J-774.1 responds to endotoxin with synthesis of thromboplastin apoprotein. The response develops in the absence of added lymphocytes and there is no increased responsiveness in cocultures of J-774.1 cells and BALB/c lymphocytes. J-774.1 cells therefore do not depend on lymphocyte cooperation for their response to endotoxin.
已建立的小鼠巨噬细胞系J-774.1对内毒素的反应是合成凝血活酶载脂蛋白。该反应在不添加淋巴细胞的情况下发生,并且在J-774.1细胞与BALB/c淋巴细胞的共培养物中没有增强的反应性。因此,J-774.1细胞对内毒素的反应不依赖于淋巴细胞的协同作用。