Fuhrmann M, Hruby K, Lenz K, Korninger C, Kyrle P A
Wien Klin Wochenschr. 1982 Mar 19;94(6):150-3.
Over the past 8 years the Poison Information Centre of Vienna was confronted 24 times with acute chlorproxithene (CPTX) poisoning. In adults doses of 2 g and more caused severe intoxication, but serious toxic manifestations were observed already at low dosage in children (after the ingestion of less than 5 mg/kg body weight). In one case unexpected death due to cardiac failure occurred as long as 49 hours after CPTX intake. The favorable outcome in one patient treated with gut, as well as gastric lavage indicates that this therapeutic strategy may be of value in the management of CPTX intoxication.
在过去8年中，维也纳中毒信息中心共接到24次急性氯普昔烯（CPTX）中毒报告。在成年人中，2克及以上剂量会导致严重中毒，但在儿童中，低剂量（摄入低于5毫克/千克体重）时就已观察到严重的毒性表现。有一例在摄入CPTX后长达49小时因心力衰竭意外死亡。一名接受肠道及洗胃治疗的患者预后良好，这表明该治疗策略在CPTX中毒的处理中可能具有价值。
