Klingler D, Bibl D
Wien Med Wochenschr. 1982 Apr 15;132(7):149-53.
The aim of this study was to determine the influence of the time of onset of therapy with cortisone, antirheumatics and diuretics with respect to successful prevention of secondary lesions by compression of the nerve fibres. Onset of therapy was considered to be "in time" on all cases with incomplete facial paralysis without appearance of electromyographic signs of denervation within the subsequent three days. The results are based on 90 patients with follow-up examination out of a total of 130 patients treated. 94% of the patients thus treated "in time" showed full or almost complete remission. Only 59% of those patients in whom the therapy was not initiated "in time" showed satisfactory results. It may be concluded that the therapy of an idiopathic facial paralysis should commence at the very first clinical signs. The differing therapeutic results reported in the literature are in part due to the problem of the sufficiently early onset of therapy.
本研究的目的是确定使用可的松、抗风湿药和利尿剂进行治疗的起始时间对成功预防神经纤维受压继发损伤的影响。对于所有不完全性面瘫且在随后三天内未出现失神经支配肌电图征象的病例，治疗起始时间被视为“及时”。结果基于130例接受治疗的患者中的90例进行了随访检查。如此“及时”接受治疗的患者中有94%显示完全或几乎完全缓解。而那些未“及时”开始治疗的患者中只有59%显示出满意的结果。可以得出结论，特发性面瘫的治疗应在出现最初临床症状时就开始。文献中报道的不同治疗结果部分归因于治疗起始时间不够早的问题。
