Liebetrau G, Pielesch W, Tuschy U
Z Gesamte Inn Med. 1982 Apr 1;37(7):218-20.
In two patients with diabetes insipidus the development of an allergic alveolitis with transition into pulmonary fibrosis could be observed. The alveolitis is evoked by snuffing of posterior pituitary extracts. The pathomechanism of this side effect (disease) is similar to those of other allergic alveolitides (e.g. farmer's lung, bird-fancier's lung, malt-worker's lung etc). This disease can be avoided by changing the therapy of diabetes insipidus to fully synthetic preparations free of protein. When irreversible changes are already present at the stroma of the lung (X-ray picture, function of the lung, histology), then the therapeutic possibilities are restricted and the prognosis is unfavourable.
在两名尿崩症患者中，可观察到过敏性肺泡炎的发生并进展为肺纤维化。这种肺泡炎是由吸入垂体后叶提取物引起的。这种副作用（疾病）的发病机制与其他过敏性肺泡炎（如农民肺、养鸟人肺、麦芽工人肺等）相似。通过将尿崩症的治疗改为完全不含蛋白质的合成制剂，可以避免这种疾病。当肺部基质已经出现不可逆变化（X线影像、肺功能、组织学）时，治疗可能性受限，预后不佳。
