Oddoy A, Joschko K
Zentralbl Gynakol. 1982;104(7):415-21.
Two doses of fenoterol (Partusisten), a beta-mimetic drug were administered by continuous intravenous infusion over 90 minutes to 20 women in advanced pregnancy, ten of them with hypertension and the other ten with normal blood pressure. Blood pressure and maternal heart rate were measured in two-minute intervals. Foetal heart rate, short term irregularity, accelerations, and foetal movements were recorded by external cardiotocography. Decrease in diastolic blood pressure in response to fenoterol in pregnant women with hypertension was more strongly pronounced than it was in normotensive women. Hence, mean pressure was reduced in the first group. while the rise in maternal heart rate was one and the same in either group. While foetal heart rates went up in both groups. the rise started earlier and with higher intensity in the normotensive group. Pregnant women with normal blood pressure also exhibited a trend to more foetal movements. Short term irregularity and area of accelerations and acceleration remained unchanged in both groups.
对20名晚期妊娠妇女持续静脉输注两剂间羟舒喘宁（Partusisten），一种β-拟似药物，输注时间为90分钟，其中10名患有高血压，另外10名血压正常。每隔两分钟测量一次血压和孕妇心率。通过外部胎心监护记录胎儿心率、短期不规则性、加速度和胎儿运动。高血压孕妇对间羟舒喘宁的舒张压下降比血压正常的孕妇更明显。因此，第一组的平均血压降低，而两组孕妇心率的上升幅度相同。虽然两组胎儿心率均上升，但血压正常组的上升开始得更早且强度更高。血压正常的孕妇胎儿运动也有增多的趋势。两组的短期不规则性以及加速度和加速面积均保持不变。
