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[应用皮层生物电位远程同步技术对精神分裂症患者联想活动的研究]

[Study of the associative activity of schizophrenic patients by the technic of remote synchronization of cortical biopotentials].

作者信息

Sviderskaia N E, Kurashov A S, Bardenshteĭn L M

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1982;82(5):76-82.

PMID:7102203
Abstract

To reveal physiological correlates of the schizophrenic thinking peculiarities associated with impaired mechanisms of information selection, spatial synchronization of the cortical biopotentials was studied in 10 healthy probands and 9 patients with continuously progressing schizophrenia. Both the healthy probands and the patients were asked to solve problems of comparing notions in situations where standard or non-standard criteria for the solution could be chosen. The bioelectrical activity was recorded at 48 cortical sites with subsequent estimation of the cross-correlation interconnections between the EEGs. It was found that in the solution of problems with the use of standard criteria the spatial-temporary organization of the biopotentials differed but little in the healthy probands and the patients, whereas in the solution of problems for which secondary, latent features of the subjects were required, these differences were rather marked in a number of characteristics, such as the general level of the synchronism, the character of interhemispheral asymmetries, the topographic distribution of the biopotential synchronization. The data obtained are discussed in the light of the present-day concepts on the functional specialization of the hemispheres.

摘要

为揭示与信息选择机制受损相关的精神分裂症思维特征的生理关联,对10名健康受试者和9名持续性进展型精神分裂症患者的皮质生物电位空间同步性进行了研究。要求健康受试者和患者在可选择标准或非标准解决标准的情况下解决概念比较问题。在48个皮质位点记录生物电活动,随后估计脑电图之间的互相关联。结果发现,在使用标准标准解决问题时,健康受试者和患者的生物电位时空组织差异不大,而在解决需要受试者次要、潜在特征的问题时,这些差异在一些特征上相当明显,如同步的总体水平、半球间不对称的特征、生物电位同步的地形分布。根据目前关于半球功能特化的概念对所得数据进行了讨论。

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