Polishchuk Iu I
Zh Nevropatol Psikhiatr Im S S Korsakova. 1982;82(5):98-102.
Clinical and statistical studies of 800 case histories of schizophrenia with an unfavourable (400 patients) and slow-progredient (400 patients) course with due regard for objective anamnestic data and findings of neurological examination revealed a significant and substantial difference in the occurrence of some exogenous factors. In the patients with schizophrenia running an unfavourable course, chronic otitis occurred 15 times more frequently, severe childhood infections 4.5 times, rheumatic fever 2.2 times, pathology of pregnancy and birth 2 times more frequently. The same patients demonstrated a 10-time more frequent occurrence of residual phenomena of organic brain injury. The data obtained might attest to the possibility of the effect of the factors cited on the severity of schizophrenia.
对800例精神分裂症病史进行临床和统计研究，其中400例病程不利，400例病程进展缓慢，并适当考虑客观的既往史数据和神经学检查结果，结果显示某些外部因素的发生率存在显著且实质性的差异。在病程不利的精神分裂症患者中，慢性中耳炎的发生率高15倍，严重儿童期感染高4.5倍，风湿热高2.2倍，妊娠和分娩病理高2倍。同样这些患者中，有机脑损伤残留现象的发生率高10倍。所获得的数据可能证明上述因素对精神分裂症严重程度有影响。
