Erikssen J, Thaulow E, Myhre E
Acta Med Scand. 1982;211(4):243-8. doi: 10.1111/j.0954-6820.1982.tb01938.x.
Coronary heart disease (CHD), previously neither diagnosed nor suspected, was strongly suspected in 115 of 2014 men aged 40-59 years during a cardiovascular survey examination. Sixty-nine of 105 men who underwent diagnostic coronary angiography had pathologic angiograms. Twenty-six of these 69 had angina pectoris (AP) with and without pathologic exercise ECGs and 43 had pathologic exercise ECG as the only indicator of CHD. The extent of coronary artery changes was similar in the two groups. The men without AP were in almost all respects similar to 1832 men labelled as normals. The men with AP differed in several respects from their non-AP angiographic counterparts and from their non-AP angiographic counterparts and from the normals: they had more dyspepsia, a higher stress score, higher serum cholesterol and triglycerides, lower antithrombin III levels in the blood and lower blood platelet retention values. These results indicate that coronary artery disease with and without AP may represent somewhat different pathogenetic entities.
在一项心血管调查检查中，2014名40 - 59岁男性中，有115人此前未被诊断或怀疑患有冠心病，但此次被高度怀疑患有该病。在接受诊断性冠状动脉造影的105名男性中，69人血管造影结果呈病理性。这69人中，26人有或无病理性运动心电图的心绞痛（AP），43人以病理性运动心电图作为冠心病的唯一指标。两组冠状动脉变化程度相似。无AP的男性在几乎所有方面与1832名被标记为正常的男性相似。有AP的男性在几个方面与其无AP血管造影的对应者以及正常男性不同：他们有更多消化不良症状、更高的压力评分、更高的血清胆固醇和甘油三酯水平、血液中抗凝血酶III水平更低以及血小板滞留值更低。这些结果表明，有或无AP的冠状动脉疾病可能代表了有所不同的致病实体。
