Frand M, Koren G, Rubinstein Z
Am J Dis Child. 1982 Aug;136(8):687-9. doi: 10.1001/archpedi.1982.03970440031008.
We treated two patients with congenital cyanotic heart disease (CCDH) in whom associated hypertrophic osteoarthropathy (HOA) developed. Both were severely cyanotic and hypoxic for many years before HOA was fully manifested. Clinical and roentgenographic indications of bone and joint lesions disappeared completely shortly after corrective of palliative surgery. There appears to be an etiologic connection between HOA and CCHD.
我们治疗了两名患有先天性青紫型心脏病（CCDH）且并发肥厚性骨关节病（HOA）的患者。在HOA完全显现之前，两人多年来一直严重青紫且缺氧。在进行矫正或姑息性手术后不久，骨与关节病变的临床及X线表现完全消失。HOA与CCHD之间似乎存在病因学联系。
