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神经系统疾病:肌萎缩侧索硬化症、重症肌无力、多发性硬化症和小儿麻痹症。

Neurologic disorders: amyotrophic lateral sclerosis, myasthenia gravis, multiple sclerosis, and poliomyelitis.

作者信息

Garfinkle T J, Kimmelman C P

出版信息

Am J Otolaryngol. 1982 May-Jun;3(3):204-12. doi: 10.1016/s0196-0709(82)80056-2.

DOI:10.1016/s0196-0709(82)80056-2
PMID:7102959
Abstract

The patient who has multiple cranial neuropathies may pose a diagnostic dilemma. The neurologic disorders of amyotrophic lateral sclerosis, multiple sclerosis, myasthenia gravis, and poliomyelitis often cause bulbar dysfunctions such as diplopia, facial weakness, slurred or hypernasal speech, dysphagia, and hoarseness. In general, treatment is supportive and is directed toward restoring or aiding lost function (i.e., tracheostomy, esophagostomy, and cricopharyngeal myotomy). The relative infrequency of these disorders can lead to delays in diagnosis and rehabilitative therapy.

摘要

患有多种颅神经病变的患者可能会带来诊断难题。肌萎缩侧索硬化症、多发性硬化症、重症肌无力和脊髓灰质炎等神经系统疾病常导致延髓功能障碍,如复视、面部无力、言语含糊或鼻音过重、吞咽困难和声音嘶哑。一般来说,治疗以支持性为主,旨在恢复或辅助丧失的功能(即气管切开术、食管造口术和环咽肌切开术)。这些疾病相对罕见,可能导致诊断和康复治疗的延迟。

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引用本文的文献

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Bulbar onset amyotrophic lateral sclerosis: A case report.延髓起病的肌萎缩侧索硬化症:一例报告。
Ann Med Surg (Lond). 2022 Nov 13;84:104889. doi: 10.1016/j.amsu.2022.104889. eCollection 2022 Dec.
2
Amyotrophic Lateral Sclerosis and Myasthenia Gravis Overlap Syndrome: A Review of Two Cases and the Associated Literature.肌萎缩侧索硬化症与重症肌无力重叠综合征:两例病例及相关文献综述
Front Neurol. 2017 May 22;8:218. doi: 10.3389/fneur.2017.00218. eCollection 2017.