Vincent J P, Choinet C, Durand M, Berjal G, Bodak A, Hatt P Y
Ann Med Interne (Paris). 1982;133(3):160-3.
Amyloid diseases include a widely dispersed group of conditions. A part from secondary, primary, and familial amyloid diseases, and those due to endocrine tumours of the APUD system, there is a tendency to isolate a group of senile amyloid diseases affecting mainly the heart. A study in a series of 923 elderly subjects demonstrated a negative correlation between amyloid disease and atheromatosis. As certain secondary amyloid diseases, particularly those secondary to myeloma, are, inversely, sometimes associated with rapidly developing atherosclerosis, this suggests the need for further studies to define the relationship between the two processes.
淀粉样变性疾病包括一组广泛分布的病症。除了继发性、原发性和家族性淀粉样变性疾病,以及那些由APUD系统内分泌肿瘤引起的疾病外,有一种趋势是将主要影响心脏的一组老年淀粉样变性疾病分离出来。一项对923名老年受试者的研究表明,淀粉样变性疾病与动脉粥样硬化之间呈负相关。由于某些继发性淀粉样变性疾病,特别是继发于骨髓瘤的疾病,有时反而与快速发展的动脉粥样硬化有关,这表明需要进一步研究来确定这两个过程之间的关系。