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印度西北部的遗传异质性与种群结构

Genetic heterogeneity and population structure in north-west India.

作者信息

Papiha S S, Mukherjee B N, Chahal M S, Malhotra K C, Roberts D F

出版信息

Ann Hum Biol. 1982 May-Jun;9(3):235-51. doi: 10.1080/03014468200005731.

DOI:10.1080/03014468200005731
PMID:7103405
Abstract

Genetic markers consisting of 11 blood group and red cell enzyme systems were investigated in 14 endogamous groups of north-west India. Genetic differentiation among the samples as indicated by FST is appreciable, reflecting the ethnic diversity characteristic of this region. Local variation within each state is lower, indicating a geographical component to the total variation. This variation is refined by calculations of genetic distances, which show that the tribals and low-caste groups are closer together but well separated from high-caste Brahmins and other non-tribal middle castes. There is a slight possibility of disruptive selection, but the analyses suggest that the differences in genetic structure in north-west India are more likely to be due to their breeding structure, differential migration and ethnic affiliation.

摘要

在印度西北部的14个同族通婚群体中,对由11个血型和红细胞酶系统组成的遗传标记进行了研究。FST表明样本之间的遗传分化显著,反映了该地区种族多样性的特征。每个邦内的局部变异较低,表明总体变异存在地理因素。通过计算遗传距离对这种变异进行了细化,结果显示部落群体和低种姓群体更为接近,但与高种姓婆罗门和其他非部落中间种姓群体有明显区分。存在轻微的间断性选择可能性,但分析表明,印度西北部遗传结构的差异更可能是由于其繁殖结构、不同的迁移情况和种族归属。

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