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1
Binding studies of a sialic acid-specific lectin from the horseshoe crab Carcinoscorpius rotunda cauda with various sialoglycoproteins.圆尾鲎（Carcinoscorpius rotunda cauda）中一种唾液酸特异性凝集素与多种唾液酸糖蛋白的结合研究。
Biochem J. 1982 Apr 1;203(1):253-61. doi: 10.1042/bj2030253.
2
Isolation and characterisation of a sialic acid-binding lectin (carcinoscorpin) from Indian horseshoe crab Carcinoscorpius rotunda cauda.从印度圆尾鲎（Carcinoscorpius rotunda cauda）中分离并鉴定一种唾液酸结合凝集素（鲎素）。
Biochim Biophys Acta. 1980 May 29;623(1):89-97. doi: 10.1016/0005-2795(80)90011-2.
3
Lectin-binding assay by polyethylene glycol 8000.用聚乙二醇8000进行凝集素结合测定。
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4
Further characterization of the sialic acid-binding lectin from the horseshoe crab Carcinoscorpius rotunda cauda.圆尾鲎中唾液酸结合凝集素的进一步特性研究。
Arch Biochem Biophys. 1981 Jun;209(1):325-33. doi: 10.1016/0003-9861(81)90288-5.
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Isolation and characterization of a sialic acid-specific binding lectin from the hemolymph of Asian horseshoe crab, Tachypleus tridentatus.从中国鲎（Tachypleus tridentatus）血淋巴中分离和鉴定一种唾液酸特异性结合凝集素。
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Carbohydrate chain analysis by lectin binding to electrophoretically separated glycoproteins from murine B16 melanoma sublines of various metastatic properties.通过凝集素与来自具有不同转移特性的小鼠B16黑色素瘤亚系的电泳分离糖蛋白结合进行碳水化合物链分析。
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Circular dichroism studies on carcinoscorpin, the sialic acid binding lectin of horseshoe crab, Carcinoscorpius rotundacauda.圆二色性研究鲎（圆尾鲎）的癌毒素，一种结合唾液酸的凝集素。
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Isolation and characterization of a sialic acid-specific lectin from hemolymph of the Southeast Asian horseshoe crab Tachypleus gigas.从东南亚鲎（Tachypleus gigas）血淋巴中分离和鉴定一种唾液酸特异性凝集素。
Biosci Biotechnol Biochem. 1993 Aug;57(8):1237-42. doi: 10.1271/bbb.57.1237.

本文引用的文献

1
Photometric determination of sialic acids in serum and cerebrospinal fluid with the thiobarbituric acid method.用硫代巴比妥酸法光度测定血清和脑脊液中的唾液酸。
Clin Chim Acta. 1962 Jul;7:467-75. doi: 10.1016/0009-8981(62)90086-4.
2
Studies on mucoproteins. VII. The linkage of the prosthetic group to aspartic and glutamic acid residues in bovine submaxillary gland mucoprotein.粘蛋白研究。VII. 牛颌下腺粘蛋白中辅基与天冬氨酸和谷氨酸残基的连接
Biochim Biophys Acta. 1961 Sep 16;52:349-60. doi: 10.1016/0006-3002(61)90684-9.
3
The thiobarbituric acid assay of sialic acids.唾液酸的硫代巴比妥酸测定法。
J Biol Chem. 1959 Aug;234(8):1971-5.
4
Resolution of microheterogeneity in rat liver acid phosphatase using immobilised sialic acid binding lectin.
Indian J Biochem Biophys. 1981 Jun;18(3):177-81.
5
Further characterization of the sialic acid-binding lectin from the horseshoe crab Carcinoscorpius rotunda cauda.圆尾鲎中唾液酸结合凝集素的进一步特性研究。
Arch Biochem Biophys. 1981 Jun;209(1):325-33. doi: 10.1016/0003-9861(81)90288-5.
6
Specificity of twelve lectins towards oligosaccharides and glycopeptides related to N-glycosylproteins.十二种凝集素对与N-糖基化蛋白相关的寡糖和糖肽的特异性。
Eur J Biochem. 1981 Jun;117(1):41-55. doi: 10.1111/j.1432-1033.1981.tb06300.x.
7
Specificities of limulin and wheat-germ agglutinin towards some derivatives of GM3 gangliosides.
Eur J Biochem. 1981;114(1):11-6. doi: 10.1111/j.1432-1033.1981.tb06164.x.
8
Limulin: a C-reactive protein from Limulus polyphemus.鲎试剂：一种来自美洲鲎的C反应蛋白。
J Biol Chem. 1981 Jan 25;256(2):969-75.
9
Fractionation of sialoglycoproteins on an immobilized sialic acid-binding lectin.
Anal Biochem. 1981 Jul 15;115(1):130-7. doi: 10.1016/0003-2697(81)90535-2.
10
Multivalent interaction between asialofetuin and plasma membrane preparations from the rat liver.
Can J Biochem. 1980 Dec;58(12):1414-20. doi: 10.1139/o80-191.

圆尾鲎（Carcinoscorpius rotunda cauda）中一种唾液酸特异性凝集素与多种唾液酸糖蛋白的结合研究。

Binding studies of a sialic acid-specific lectin from the horseshoe crab Carcinoscorpius rotunda cauda with various sialoglycoproteins.

作者信息

Mohan S, Thambi Dorai D, Srimal S, Bachhawat B K

出版信息

Biochem J. 1982 Apr 1;203(1):253-61. doi: 10.1042/bj2030253.

DOI:10.1042/bj2030253
PMID:7103938
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1158217/
Abstract

Interaction of the sialic acid-specific lectin carcinoscorpin with various sialoglycoproteins was studied by using radioiodinated lectin. The binding of carcinoscorpin was dependent not only on sialic acid content but also on the type of glycosidic linkage and form (branched or linear) of the carbohydrate chains. Carcinoscorpin has different classes of binding sites, and binding follows a phenomenon of positive co-operativity. The effect of Ca2+ concentration on the binding was studied, and the optimal concentration was found to be 0.02 M. Effect of pH, temperature and other bivalent metal ions are also reported. From haemagglutination- and precipitation-inhibition studies, it was concluded that carcinoscorpin has multispecificity towards acidic sugars, and its relation to the biological role of the lectin in the horseshoe crab is discussed.

摘要

利用放射性碘化凝集素研究了唾液酸特异性凝集素癌蟹素与各种唾液酸糖蛋白的相互作用。癌蟹素的结合不仅取决于唾液酸含量，还取决于碳水化合物链的糖苷键类型和形式（分支或线性）。癌蟹素有不同类型的结合位点，且结合呈现正协同效应。研究了Ca2+浓度对结合的影响，发现最佳浓度为0.02 M。还报道了pH、温度和其他二价金属离子的影响。通过血凝抑制和沉淀抑制研究得出结论，癌蟹素对酸性糖具有多特异性，并讨论了其与鲎中凝集素生物学作用的关系。