Suppr超能文献

A 1H nuclear-magnetic-resonance study of the solution conformation of the isoinhibitor K from Helix pomatia.

作者信息

Wagner G, Wüthrich K, Tschesche H

出版信息

Eur J Biochem. 1978 Sep 1;89(2):367-77. doi: 10.1111/j.1432-1033.1978.tb12538.x.

DOI:10.1111/j.1432-1033.1978.tb12538.x
PMID:710398
Abstract

The isoinhibitor K from Helix pomatia was investigated by high-resolution 1H nuclear magnetic resonance at 360 MHZ. Detailed studies of the labile protons and the resonances of the aromatic residues indicated extensive homologies between the spatial structures of the snail inhibitor, the basic pancreatic trypsin inhibitor (Kunitz) from bovine tissue and the cos colostrum trypsin inhibitor. Comparison of these three homologous inhibitors indicated that the overall flexibility of the globular protein conformation is reduced and its stability with respect to thermal denaturation raised when the content of amino acids with charged side chains is increased. It is suggested that this relation between amino acid composition and stability of the globular solution structure might be valid also for other classes of homologous proteins.

摘要

相似文献

1
A 1H nuclear-magnetic-resonance study of the solution conformation of the isoinhibitor K from Helix pomatia.
Eur J Biochem. 1978 Sep 1;89(2):367-77. doi: 10.1111/j.1432-1033.1978.tb12538.x.
2
A 1H nuclear-magnetic-resonance study of the conformation and the molecular dynamics of the glycoprotein cow-colostrum trypsin inhibitor.糖蛋白牛初乳胰蛋白酶抑制剂的构象和分子动力学的1H核磁共振研究。
Eur J Biochem. 1978 May;86(1):67-76. doi: 10.1111/j.1432-1033.1978.tb12285.x.
3
Trypsin-kallikrein isoinhibitor K (type Kunitz) from snails (Helix pomatia). Purification and characterization.蜗牛（玛瑙螺）的胰蛋白酶-激肽释放酶异抑制剂K（库尼茨型）。纯化与特性鉴定。
Eur J Biochem. 1975 Oct 15;58(2):453-60. doi: 10.1111/j.1432-1033.1975.tb02392.x.
4
The amino-acid sequence of isoinhibitor K form snails (Helix pomatia). A sequence determination by automated Edman degradation and mass-spectral identification of the phenylthiohydantoins.
Eur J Biochem. 1975 Oct 15;58(2):439-51. doi: 10.1111/j.1432-1033.1975.tb02391.x.
5
[The disulfide bridges of the trypsin-kallikrein inhibitor K from snails (Helix pomatia). Thermal inactivation and proteolysis by thermolysin (author's transl)].[蜗牛（罗马蜗牛）胰蛋白酶-激肽释放酶抑制剂K的二硫键。热失活及嗜热菌蛋白酶的蛋白水解作用（作者译）]
Hoppe Seylers Z Physiol Chem. 1976 Feb;357(2):139-45.
6
1H-NMR studies of the structure and stability of the bovine pancreatic secretory trypsin inhibitor.牛胰分泌型胰蛋白酶抑制剂结构与稳定性的1H-核磁共振研究
J Biol Chem. 1982 Jul 25;257(14):8337-42.
7
Assignment of the 1H nuclear magnetic resonance spectrum of the trypsin inhibitor homologue K from Dendroaspis polylepis polylepis. Two-dimensional nuclear magnetic resonance at 360 and 500 MHz.多鳞树眼镜蛇胰蛋白酶抑制剂同系物K的1H核磁共振谱的归属。360和500兆赫的二维核磁共振。
J Mol Biol. 1983 Feb 5;163(4):623-46. doi: 10.1016/0022-2836(83)90115-8.
8
1H nuclear-magnetic-resonance studies of the porcine-pancreatic secretory trypsin inhibitor at 270 MHz.在270兆赫频率下对猪胰分泌型胰蛋白酶抑制剂进行的质子核磁共振研究。
Eur J Biochem. 1979 Dec;102(1):185-94. doi: 10.1111/j.1432-1033.1979.tb06279.x.
9
Trypsin-kallikrein inhibitors from snails (Helix pomatia).
Methods Enzymol. 1976;45:772-85. doi: 10.1016/s0076-6879(76)45070-x.
10
Correlations between internal mobility and stability of globular proteins.球状蛋白质内部流动性与稳定性之间的相关性。
Biophys J. 1980 Oct;32(1):549-60. doi: 10.1016/S0006-3495(80)84989-7.

引用本文的文献

1
Correlations between internal mobility and stability of globular proteins.球状蛋白质内部流动性与稳定性之间的相关性。
Biophys J. 1980 Oct;32(1):549-60. doi: 10.1016/S0006-3495(80)84989-7.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验