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孤立的C3系膜沉积物是否可导致肾小球血尿性肾病(作者译)

[Could isolated mesangial deposits of C3 be responsible of glomerular hematuric nephropathies (author's transl)].

作者信息

Saint-Andre J P, Touzard D, Houssin A, Simard C

出版信息

Ann Pathol. 1982;2(2):159-62.

PMID:7104070
Abstract

This communication presents three cases of prolonged macroscopic hematuria in young subjects. Complementary explorations eliminated urologic or vascular causes. Renal biopsies showed minimal glomerular lesions with light microscopy, normal basement membranes in electron microscopy and mesangial deposits of C3 and properdine in immunofluorescence. Although the mesangial deposits of C3 lack specificity and the number of observations is small, it appears useful to report such cases so as to indicate their frequency and perhaps their autonomy, in glomerular hematuric nephropathies.

摘要

本通讯介绍了3例年轻患者长期肉眼血尿的病例。辅助检查排除了泌尿系统或血管方面的病因。肾活检显示,光镜下肾小球病变轻微,电镜下基底膜正常,免疫荧光显示C3和备解素在系膜沉积。尽管C3在系膜沉积缺乏特异性且观察病例数较少,但报告此类病例似乎有助于指出其在肾小球性血尿肾病中的发生率以及可能的独立性。

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