吲哚洛尔和普萘洛尔对高血压患者肾功能的影响。
Effect of pindolol and propranolol on renal function of patients with hypertension.
作者信息
Pasternack A, Pörsti P, Pöyhönen L
出版信息
Br J Clin Pharmacol. 1982;13(Suppl 2):241S-244S. doi: 10.1111/j.1365-2125.1982.tb01921.x.
Abstract
1 Pindolol and propranolol were administered orally in equipotent antihypertensive doses to 14 subjects with mild to moderate hypertension in an open cross-over study. 2 Pindolol caused a smaller decrease in plasma renin activity and heart rate than propranolol. 3 Glomerular filtration rate and effective renal plasma flow remained unchanged during therapy with either agent.
摘要
在一项开放性交叉研究中，给14名轻度至中度高血压患者口服等效降压剂量的吲哚洛尔和普萘洛尔。
吲哚洛尔引起的血浆肾素活性和心率下降幅度比普萘洛尔小。
用这两种药物治疗期间，肾小球滤过率和有效肾血浆流量均保持不变。
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