Kato H, Morioka H, Tsutsui H, Aramaki S, Torigoe T
Cancer. 1982 Oct 1;50(7):1294-6. doi: 10.1002/1097-0142(19821001)50:7<1294::aid-cncr2820500712>3.0.co;2-k.
The value of a tumor-antigen (TA-4) of squamous cell carcinoma in evaluating the extent of disease was studied in patients who primarily had surgical treatments with a diagnosis of cervical squamous cell carcinoma. Pretreatment serum TA-4 levels were determined by a radioimmunoassay method. The extent of disease was determined by surgical evaluation and postoperative histologic examinations. Furthermore, all patients were followed for at least two years, and those patients who developed recurrence at the sites which were unresectable by radical hysterectomy were retrospectively regarded as the unresectable case. It was found that serum TA-4 levels reflected the extent of disease, and that high pretreatment TA-4 levels indicated the presence of the widespread tumor which was unresectable by radical hysterectomy.
在主要接受手术治疗且诊断为宫颈鳞状细胞癌的患者中，研究了鳞状细胞癌肿瘤抗原（TA - 4）在评估疾病范围方面的价值。术前血清TA - 4水平通过放射免疫测定法测定。疾病范围通过手术评估和术后组织学检查确定。此外，所有患者至少随访两年，那些在根治性子宫切除无法切除的部位出现复发的患者被回顾性地视为不可切除病例。结果发现，血清TA - 4水平反映了疾病范围，术前TA - 4水平高表明存在根治性子宫切除无法切除的广泛肿瘤。
