Ippen H, Korts G
Derm Beruf Umwelt. 1982;30(3):73-5.
A patient suffering extensive burns on the back of the head from a heavy current accident in 1946 later had to undergo a craniotomy in this region. An ulcer later formed in the scar leading to a great defect of the cranial bone. 35 years after the accident a squamous cell carcinoma was established for the first time in the rim of the scar ulcer. The patient died in August 1981 of an acute coronary-artery insufficiency. In the autopsy an osteomalacia of the whole cranial bone after removal by operation of a horny squamous cell carcinoma, as well as a cerebral malacia were found. Based on the literature (31 references) on relations between burn scars and the later formation of carcinoma, the carcinoma was recognised as resulting from the accident.
一名患者在1946年因一次强电流事故导致头部后部大面积烧伤，后来不得不在该区域接受开颅手术。随后瘢痕处形成溃疡，导致颅骨出现巨大缺损。事故发生35年后，瘢痕溃疡边缘首次确诊为鳞状细胞癌。该患者于1981年8月死于急性冠状动脉供血不足。尸检发现，在切除角质鳞状细胞癌后，整个颅骨出现骨软化，同时还有脑软化。根据关于烧伤瘢痕与后期癌症形成之间关系的文献（31篇参考文献），该癌症被认定为由此次事故导致。
