Erskine M S, Baum M J
Endocrinology. 1982 Sep;111(3):767-72. doi: 10.1210/endo-111-3-767.
Concentrations of testosterone (T) and 5 alpha-dihydrotestosterone (DHT) were measured in plasma collected from male and female ferrets at eight perinatal ages, spanning the period when behavioral sexual differentiation occurs in this species. Concentrations of T were significantly higher in males than in females 5 days before birth (day -5) and on postnatal days 10, 15, and 40. Plasma concentrations of DHT were equivalent in both sexes at all ages. In males, mean plasma T (2,278 pg/ml) and DHT (1,989 pg/ml) concentrations were highest on day -5, and declined significantly by postnatal day 5. In females, plasma concentrations of T (1,220 pg/ml) were highest on the day of birth, whereas concentrations of DHT (1,896 pg/ml) were highest on day -5; both declined significantly by postnatal day 5. The mean concentrations of T and DHT in sera from reproductively active adult male ferrets were 26,019 and 888 pg/ml, respectively, whereas sera from seasonally quiescent males contained 2,976 pg/ml T and 252 pg/ml DHT. The results demonstrate that circulating concentrations of T are significantly higher in male than in female ferrets at those neonatal ages when, in other experiments, T administration to females permanently augmented their ability to display masculine coital behavior in adulthood.
在围产期八个不同年龄阶段采集雄性和雌性雪貂的血浆，测定睾酮（T）和5α-双氢睾酮（DHT）的浓度，这八个阶段涵盖了该物种行为性分化发生的时期。在出生前5天（-5日）以及出生后第10、15和40天，雄性雪貂的T浓度显著高于雌性。在所有年龄阶段，两性的血浆DHT浓度相当。雄性雪貂中，血浆T平均浓度（2278 pg/ml）和DHT平均浓度（1989 pg/ml）在-5日时最高，到出生后第5天显著下降。雌性雪貂中，血浆T浓度（1220 pg/ml）在出生当天最高，而DHT浓度（1896 pg/ml）在-5日时最高；两者到出生后第5天均显著下降。生殖活跃的成年雄性雪貂血清中T和DHT的平均浓度分别为26019 pg/ml和888 pg/ml，而季节性静止期雄性雪貂的血清中T浓度为2976 pg/ml，DHT浓度为252 pg/ml。结果表明，在其他实验中，给雌性雪貂注射T可使其成年后永久增强表现出雄性交配行为的能力，在那些新生儿期，雄性雪貂的循环T浓度显著高于雌性。
