利用四倍体变色树蛙（Hyla versicolor）中苹果酸脱氢酶基因座对配子分离多态性的证据。
Evidence for a polymorphism in gametic segregation using a malate dehydrogenase locus in the tetraploid treefrog Hyla versicolor.
作者信息
Danzmann R G, Bogart J P
出版信息
Genetics. 1982 Feb;100(2):287-306. doi: 10.1093/genetics/100.2.287.
Abstract
Artificial cross combinations of tetraploid Hyla versicolor were analyzed electrophoretically using a polymorphic malate dehydrogenase locus (MDH-1) to determine the mechanism of chromosome segregation. Models for differentiating between disomic and tetrasomic inheritance are presented and tested. In some crosses progeny genotypes fit a disomic mode of segregation. In other crosses there is only evidence for a tetrasomic mode of segregation. Additional crosses produced genotypic ratios which conformed to either a disomic or tetrasomic mode of segregation. The same type of inheritance was demonstrated for any individual when used in multiple cross combinations. These results suggest that there exists in H. versicolor a polymorphism with respect to segregation of gametes, resulting from differences in chromosome pairings during meiosis I.
摘要
利用一个多态性苹果酸脱氢酶基因座（MDH - 1）对四倍体变色雨蛙的人工杂交组合进行电泳分析，以确定染色体分离机制。提出并测试了区分二体遗传和四体遗传的模型。在一些杂交中，后代基因型符合二体分离模式。在其他杂交中，只有证据支持四体分离模式。另外的杂交产生了符合二体或四体分离模式的基因型比例。当用于多个杂交组合时，任何个体都表现出相同类型的遗传。这些结果表明，变色雨蛙在配子分离方面存在多态性，这是由减数分裂I期间染色体配对的差异导致的。
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