West-Hyde L, Buyukmihci N
J Am Vet Med Assoc. 1982 Aug 1;181(3):243-7.
Blindness developed at an early age in 2 generations of cats. Findings included abnormal pupillary responses to light, tapetal hyperreflectivity, retinal vascular attenuation, and virtually extinct electroretinograms. Histologic and ultrastructural abnormalities were found only in photoreceptors. There were poor inner and outer segment development and reduction in visual cell nuclei, with concomitant narrowing of the outer plexiform layer early in the postnatal period. Eventually, there was complete loss of the photoreceptor layer. The clinical and microscopic findings suggested this retinal disease may be a heritable rod-cone dysplasia.
在两代猫中，失明在幼年时就已出现。检查结果包括瞳孔对光反应异常、脉络膜反光增强、视网膜血管变细以及几乎消失的视网膜电图。组织学和超微结构异常仅在光感受器中发现。内节和外节发育不良，视细胞细胞核减少，出生后早期外网状层随之变窄。最终，光感受器层完全丧失。临床和显微镜检查结果表明，这种视网膜疾病可能是一种遗传性视锥视杆细胞营养不良。
