Stempel J M, Duane W C
Gastroenterology. 1978 Oct;75(4):608-11.
Eight male subjects who had previously undergone vagotomy and pyloroplasty were found to have significantly larger bile acid pools than did a group of matched control subjects. Associated with these expanded pools was a significantly lower molar per cent cholesterol of gallbladder bile in the vagotomy group. These findings are the opposite of those expected in a group predisposed to cholesterol cholelithiasis, suggesting that vagotomy, at least in males, does not predispose to cholesterol gallstones. If such stones form after vagotomy, they presumably do so by a mechanism not presently appreciated.
八名先前接受过迷走神经切断术和幽门成形术的男性受试者，其胆汁酸池明显大于一组匹配的对照受试者。迷走神经切断术组中，与这些扩大的胆汁酸池相关的是胆囊胆汁中胆固醇的摩尔百分比显著降低。这些发现与易患胆固醇结石的人群预期的结果相反，表明迷走神经切断术，至少在男性中，不会增加患胆固醇结石的风险。如果在迷走神经切断术后形成了此类结石，推测其形成机制目前尚不清楚。
