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糖尿病母亲的婴儿及出生时的早产儿的中性粒细胞趋化作用。

Neutrophil chemotaxis in infants of diabetic mothers and in preterms at birth.

作者信息

Mohandes A E, Touraine J L, Osman M, Salle B

出版信息

J Clin Lab Immunol. 1982 Jun;8(2):117-20.

PMID:7108938
Abstract

The chemotaxis of polymorphonuclear leukocytes of infants of diabetic mothers and of preterms was found lower than that of full term newborns when cells were incubated in autologous serum. When leukocytes from full terms were incubated in preterm serum, chemotaxis was significantly reduced. When leukocytes from either infants of diabetic mothers or preterms were incubated with full term serum, chemotaxis was significantly increased. No difference was found between infants of diabetic mothers and preterms. These results suggest that both groups of patients have a deficiency in serum factors playing a part in chemotaxis.

摘要

当多形核白细胞在自体血清中孵育时,发现糖尿病母亲的婴儿和早产儿的多形核白细胞趋化性低于足月儿。当足月儿的白细胞在早产儿血清中孵育时,趋化性显著降低。当糖尿病母亲的婴儿或早产儿的白细胞与足月儿血清一起孵育时,趋化性显著增加。糖尿病母亲的婴儿和早产儿之间未发现差异。这些结果表明,两组患者在参与趋化作用的血清因子方面均存在缺陷。

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