Marrin C A, Rose E A, Spotnitz H M, Bregman D
J Thorac Cardiovasc Surg. 1982 Sep;84(3):426-9.
Left ventricular copulsation was evaluated as a means of circulatory support in an experimental canine cardiogenic shock preparation. Copulsation was effected by a commercially available pulsatile assist device which was attached to an apical left ventricular vent cannula. The hemodynamic effects were compared with those of intra-aortic balloon pumping (IABP) in the same animals. Copulsation produced a 35.6% increase in mean aortic blood pressure, a 32.3% reduction in mean left atrial pressure, a 66.7% increase in cardiac output, and a 76.2% increase in coronary blood flow. The improvement in these variables was significantly greater during left ventricular copulsation than during IABP (p less than 0.05). The method is simple, uses equipment that is readily available, and is potentially a powerful intermediate circulatory support modality between IABP and more complex techniques.
在一种实验性犬心源性休克模型中,评估了左心室搏动作为一种循环支持手段的效果。搏动通过一种市售的搏动辅助装置实现,该装置连接到左心室心尖引流管。将这些血流动力学效应与同一动物的主动脉内球囊反搏(IABP)的效应进行了比较。左心室搏动使平均主动脉血压升高35.6%,平均左心房压力降低32.3%,心输出量增加66.7%,冠状动脉血流量增加76.2%。与IABP相比,这些变量在左心室搏动期间的改善明显更大(p<0.05)。该方法简单,使用的设备容易获得,并且可能是IABP和更复杂技术之间一种强大的中间循环支持方式。