大鼠胆汁成分与胆汁性腹膜炎的关系
Relationship of the constituents of bile to biliary peritonitis in the rat.
作者信息
Walker E M, Ellis H
出版信息
Gut. 1978 Sep;19(9):827-30. doi: 10.1136/gut.19.9.827.
Abstract
The local action of bile salts has been associated with a wide variety of gastrointestinal diseases. This paper describes an animal model to determine which of the major solid components of bile are responsible for peritoneal destruction in biliary peritonitis. In the rat, bile salts within the peritoneal cavity cause peritonitis but cholesterol and lecithin are without deleterious effect.
摘要
胆汁盐的局部作用与多种胃肠道疾病有关。本文描述了一种动物模型，以确定胆汁的主要固体成分中哪些是导致胆汁性腹膜炎腹膜破坏的原因。在大鼠中，腹腔内的胆汁盐会引起腹膜炎，但胆固醇和卵磷脂没有有害作用。
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