Dóczi T, Tarjányi J, Huszka E, Kiss J
Neurosurgery. 1982 Jun;10(6 Pt 1):685-8. doi: 10.1227/00006123-198206010-00001.
The authors report a review of 1808 patients admitted for the treatment of craniocerebral injuries. Eighty-four (4.6%) developed the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). Two types of SIADH (severe and mild) were defined on the basis of laboratory findings and clinical signs. SIADH occurred in 0.6% of the patients with mild head injury, 10.6% of those with moderate head injury, and 4.7% of the patients with severe head injury. Regular measurements of serum electrolytes, osmolality, and urinary sodium depletion should be made during the treatment of patients suffering from head trauma because unexpected clinical deterioration may often have a reversible cause: SIADH.
作者报告了对1808例因颅脑损伤入院治疗的患者的回顾性研究。其中84例（4.6%）发生了抗利尿激素分泌不当综合征（SIADH）。根据实验室检查结果和临床体征定义了两种类型的SIADH（重度和轻度）。轻度颅脑损伤患者中SIADH的发生率为0.6%，中度颅脑损伤患者为10.6%，重度颅脑损伤患者为4.7%。在治疗头部创伤患者期间，应定期测量血清电解质、渗透压和尿钠消耗情况，因为意外的临床恶化往往可能有一个可逆的原因：SIADH。
