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[肩部快速破坏性关节病]

[Rapid destructive arthropathy of the shoulder].

作者信息

Lequesne M, Fallut M, Coulomb R, Magnet J L, Strauss J

出版信息

Rev Rhum Mal Osteoartic. 1982 May;49(6):427-37.

PMID:7112022
Abstract

Within the general context of rapid destruction of the humeral head, destructive arthropathy of the shoulder, described here in six cases, is a diagnosis of elimination. Being neither infectious inflammatory, microcrystalline, nor neurological, this curious variety of degenerative pathology of the shoulder involves the following: 1) a particular group of sufferers: women aged 65 to 81 years; 2) prior signs, at least radiological, of deterioration in the rotator cuff; 3) rapid erosive osteolysis of the head of the humerus reducing its radiological area by 25 per cent in less than six months; 4) early narrowing of the scapulo-humeral joint space (Ist to 9th month); 5) transient appearance of calcium debris in the area of the joint; 6) a synovial effusion in some cases, often bloody. The destruction phase is associated with pain lasting from two months to two years. However at the stage of stable sequelae, pain is moderate or minimal. Differential diagnosis with destructive arthropathy due to articular chondrocalcinosis and necrosis of the head of the humerus is particularly discussed. The cause of rapid destruction is unknown. It may be multifactorial: advanced age (constant), osteoporosis, fragility of articular cartilage as evidenced by multiple localizations of osteoarthrosis (4 cases out of 6), enzymes in the bloody effusion, trauma (3 cases out of 7), and intra-articular injections of corticosteroid derivatives, in particular fluorinated (3 cases out of 7) may possibly play a role.

摘要

在肱骨头快速破坏的总体背景下,本文描述的6例肩部破坏性关节病是一种排除性诊断。这种奇特的肩部退行性病变既非感染性炎症、微晶性病变,也非神经性病变,其涉及以下方面:1)特定的一组患者:65至81岁的女性;2)至少在影像学上有肩袖退变的先前迹象;3)肱骨头快速侵蚀性骨质溶解,在不到6个月的时间内其放射学面积减少25%;4)肩胛肱关节间隙早期变窄(第1至9个月);5)关节区域出现钙碎屑的短暂表现;6)在某些情况下出现滑膜积液,通常为血性。破坏阶段伴有持续2个月至2年的疼痛。然而,在稳定后遗症阶段,疼痛为中度或轻微。特别讨论了与关节软骨钙质沉着症和肱骨头坏死所致破坏性关节病的鉴别诊断。快速破坏的原因尚不清楚。可能是多因素的:高龄(始终存在)、骨质疏松、如骨关节炎多处发病所证明的关节软骨脆弱(6例中有4例)、血性积液中的酶、创伤(7例中有3例)以及关节内注射皮质类固醇衍生物,特别是含氟衍生物(7例中有3例)可能起了作用。

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