Zeng M B
Sci Sin B. 1982 Jul;25(7):725-9.
Ultrastructural changes occur in the nuclei of the presumptive ectoderm cells of the early gastrula of Cynops orientalis after treatment with a mesodermal inducing substance (guinea pig bone marrow extract). The large condensed chromatin masses in the nuclei of the control series are no longer found; they become more or less dispersed. The successive changes of chromatin from condensed to dispersed have been observed. And in connection with the observations on neural induction after Ca-free treatment, the transformation from heterochromatin to euchromatin as the initiation of cell differentiation has been discussed.
用中胚层诱导物质(豚鼠骨髓提取物)处理东方蝾螈早期原肠胚预定外胚层细胞的细胞核后,会出现超微结构变化。对照系列细胞核中可见的大的凝聚染色质团不再出现;它们或多或少变得分散。观察到染色质从凝聚到分散的连续变化。并且结合无钙处理后神经诱导的观察结果,讨论了从异染色质到常染色质的转变作为细胞分化起始的情况。