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羊水乙酰胆碱酯酶电泳在神经管缺陷产前诊断中的应用

Amniotic fluid acetylcholinesterase electrophoresis in the prenatal diagnosis of neural tube defects.

作者信息

Davidson J S, Nelson M M, Peterson E M

出版信息

S Afr Med J. 1982 Sep 18;62(13):441-2.

PMID:7112322
Abstract

Amniotic fluid acetylcholinesterase electrophoresis has become available as a test for the prenatal diagnosis of open neural tube defects. The results of acetylcholinesterase electrophoresis on 125 amniotic fluid samples, including 18 from fetuses with open neural tube defects, are presented. These results indicate that this test, in conjunction with alpha-fetoprotein measurement, is of considerable practical value.

摘要

羊水乙酰胆碱酯酶电泳已作为一种用于开放性神经管缺陷产前诊断的检测方法。本文展示了对125份羊水样本进行乙酰胆碱酯酶电泳的结果,其中包括18份来自患有开放性神经管缺陷胎儿的样本。这些结果表明,该检测方法与甲胎蛋白测量相结合具有相当大的实用价值。

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Amniotic fluid acetylcholinesterase electrophoresis in the prenatal diagnosis of neural tube defects.羊水乙酰胆碱酯酶电泳在神经管缺陷产前诊断中的应用
S Afr Med J. 1982 Sep 18;62(13):441-2.
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Prenatal diagnosis of open neural tube defects using the amniotic fluid acetylcholinesterase assay.应用羊水乙酰胆碱酯酶测定法进行开放性神经管缺陷的产前诊断。
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Gel electrophoresis of amniotic-fluid acetylcholinesterase and open neural tube defect.羊水乙酰胆碱酯酶的凝胶电泳与开放性神经管缺陷
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[The determination of acetylcholinesterase activity in amniotic fluid as a further possibility for the prenatal diagnosis of open neural tube defects].
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Amniotic-fluid acetylcholinesterase as a possible diagnostic test for neural-tube defects in early pregnancy.羊水乙酰胆碱酯酶作为孕早期神经管缺陷的一种可能诊断检测方法。
Lancet. 1979 Mar 31;1(8118):685-8. doi: 10.1016/s0140-6736(79)91144-9.